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Accurate genome-scale percentage DNA methylation estimates from microarray data

DNA methylation is a key regulator of gene function in a multitude of both normal and abnormal biological processes, but tools to elucidate its roles on a genome-wide scale are still in their infancy. Methylation sensitive restriction enzymes and microarrays provide a potential high-throughput, low-...

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Detalhes bibliográficos
Main Authors: Aryee, Martin J., Wu, Zhijin, Ladd-Acosta, Christine, Herb, Brian, Feinberg, Andrew P., Yegnasubramanian, Srinivasan, Irizarry, Rafael A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062148/
https://ncbi.nlm.nih.gov/pubmed/20858772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxq055
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