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Structural Basis for a Lethal Mutation in U6 RNA(,)

U6 RNA is essential for nuclear pre-mRNA splicing and has been implicated directly in catalysis of intron removal. The U80G mutation at the essential magnesium binding site of the U6 3′ intramolecular stem–loop region (ISL) is lethal in yeast. To further understand the structure and function of the...

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Bibliografiset tiedot
Päätekijät: Sashital, Dipali G., Allmann, Anne M., Van Doren, Steven R., Butcher, Samuel E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2003
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124365/
https://ncbi.nlm.nih.gov/pubmed/12578359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi027137h
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