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Humans differ from other hominids in lacking an activating NK cell receptor that recognizes the C1 Epitope of MHC class I
Modulation of human NK cell function by killer cell immunoglobulin-like receptors (KIR) and MHC class I is dominated by the bipartite interactions of inhibitory lineage III KIR with the C1 and C2 epitopes of HLA-C. In comparison, the ligand specificities and functional contributions of the activatin...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3124310/ https://ncbi.nlm.nih.gov/pubmed/20802150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001951 |
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