Humans differ from other hominids in lacking an activating NK cell receptor that recognizes the C1 Epitope of MHC class I

Eitemau Tebyg

• Co-evolution of Killer Cell Immunoglobulin-like Receptors with HLA-C to Become The Major Variable Regulators of Human NK cells
  gan: Aguilar, Anastazia M. Older, et al.
  Cyhoeddwyd: (2010)
• Natural variation at position 45 in the D1 domain of lineage III killer cell immunoglobulin-like receptors (KIR) has major effects on the avidity and specificity for MHC class I
  gan: Older Aguilar, Anastazia M., et al.
  Cyhoeddwyd: (2011)
• Chimpanzees use More Varied Receptors and Ligands than Humans for Inhibitory KIR Recognition of the MHC-C1 and MHC-C2 Epitopes
  gan: Moesta, Achim K., et al.
  Cyhoeddwyd: (2009)
• Mutation at Positively Selected Positions in the Binding site for HLA-C Shows KIR2DL1 is a More Refined but Less Adaptable NK cell Receptor than KIR2DL3()
  gan: Hilton, Hugo G., et al.
  Cyhoeddwyd: (2012)
• Evolution and survival of marine carnivores did not require a diversity of KIR or Ly49 NK cell receptors
  gan: Hammond, John A., et al.
  Cyhoeddwyd: (2009)