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Humans differ from other hominids in lacking an activating NK cell receptor that recognizes the C1 Epitope of MHC class I

Modulation of human NK cell function by killer cell immunoglobulin-like receptors (KIR) and MHC class I is dominated by the bipartite interactions of inhibitory lineage III KIR with the C1 and C2 epitopes of HLA-C. In comparison, the ligand specificities and functional contributions of the activatin...

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Main Authors: Moesta, Achim K., Graef, Thorsten, Abi-Rached, Laurent, Older Aguilar, Anastazia M., Guethlein, Lisbeth A., Parham, Peter
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124310/
https://ncbi.nlm.nih.gov/pubmed/20802150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001951
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