Membrane Sealant Poloxamer P188 Protects Against Isoproterenol Induced Cardiomyopathy in Dystrophin Deficient Mice

BACKGROUND: Cardiomyopathy in Duchenne muscular dystrophy (DMD) is an increasing cause of death in patients. The absence of dystrophin leads to loss of membrane integrity, cell death and fibrosis in cardiac muscle. Treatment of cardiomyocyte membrane instability could help prevent cardiomyopathy. ME...

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Главные авторы: Spurney, Christopher F, Guerron, Alfredo D, Yu, Qing, Sali, Arpana, van der Meulen, Jack H, Hoffman, Eric P, Nagaraju, Kanneboyina
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2011
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123649/
https://ncbi.nlm.nih.gov/pubmed/21575230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2261-11-20
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