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Membrane Sealant Poloxamer P188 Protects Against Isoproterenol Induced Cardiomyopathy in Dystrophin Deficient Mice

BACKGROUND: Cardiomyopathy in Duchenne muscular dystrophy (DMD) is an increasing cause of death in patients. The absence of dystrophin leads to loss of membrane integrity, cell death and fibrosis in cardiac muscle. Treatment of cardiomyocyte membrane instability could help prevent cardiomyopathy. ME...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Spurney, Christopher F, Guerron, Alfredo D, Yu, Qing, Sali, Arpana, van der Meulen, Jack H, Hoffman, Eric P, Nagaraju, Kanneboyina
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123649/
https://ncbi.nlm.nih.gov/pubmed/21575230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2261-11-20
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