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Protection of Nonself Surfaces from Complement Attack by Factor H-Binding Peptides: Implications for Therapeutic Medicine

Exposure of nonself surfaces such as those of biomaterials or transplanted cells and organs to host blood frequently triggers innate immune responses, thereby affecting both their functionality and tolerability. Activation of the alternative pathway of complement plays a decisive role in this unfavo...

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Autori principali: Wu, You-Qiang, Qu, Hongchang, Sfyroera, Georgia, Tzekou, Apostolia, Kay, Brian K., Nilsson, Bo, Ekdahl, Kristina Nilsson, Ricklin, Daniel, Lambris, John D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123137/
https://ncbi.nlm.nih.gov/pubmed/21339361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003802
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