Interplay between Ribosomal Protein S27a and MDM2 Protein in p53 Activation in Response to Ribosomal Stress

Ribosomal proteins play a critical role in tightly coordinating p53 signaling with ribosomal biogenesis. Several ribosomal proteins have been shown to induce and activate p53 via inhibition of MDM2. Here, we report that S27a, a small subunit ribosomal protein synthesized as an 80-amino acid ubiquiti...

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Detaylı Bibliyografya
Asıl Yazarlar: Sun, Xiao-Xin, DeVine, Tiffany, Challagundla, Kishore B., Dai, Mu-Shui
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2011
Konular:
Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123040/
https://ncbi.nlm.nih.gov/pubmed/21561866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.223651
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