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Ribosomal Protein L11 Recruits miR-24/miRISC To Repress c-Myc Expression in Response to Ribosomal Stress

c-Myc promotes cell growth by enhancing ribosomal biogenesis and translation. Deregulated expression of c-Myc and aberrant ribosomal biogenesis and translation contribute to tumorigenesis. Thus, a fine coordination between c-Myc and ribosomal biogenesis is vital for normal cell homeostasis. Here, we...

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Detalles Bibliográficos
Main Authors: Challagundla, Kishore B., Sun, Xiao-Xin, Zhang, Xiaoli, DeVine, Tiffany, Zhang, Qinghong, Sears, Rosalie C., Dai, Mu-Shui
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187350/
https://ncbi.nlm.nih.gov/pubmed/21807902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05810-11
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