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Outer Membrane Protein Complex of Meningococcus Enhances the Antipolysaccharide Antibody Response to Pneumococcal Polysaccharide–CRM(197) Conjugate Vaccine

Bacterial polysaccharides (PS) are T cell-independent antigens that do not induce immunologic memory and are poor immunogens in infants. Conjugate vaccines in which the PS is covalently linked to a carrier protein have enhanced immunogenicity that resembles that of T cell-dependent antigens. The Hae...

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Autori principali: Lai, Zengzu, Schreiber, John R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122513/
https://ncbi.nlm.nih.gov/pubmed/21450979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00053-11
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