CpG Oligodeoxynucleotides Act as Adjuvants for Pneumococcal Polysaccharide-Protein Conjugate Vaccines and Enhance Antipolysaccharide Immunoglobulin G2a (IgG2a) and IgG3 Antibodies

Pneumococcal polysaccharide-protein conjugate vaccines elicit antipolysaccharide antibodies, but multiple doses are required to achieve protective antibody levels in children. In addition, the immunogenicity of experimental multivalent pneumococcal conjugate vaccines varies with different polysaccha...

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Main Authors: Chu, Rose S., McCool, Tera, Greenspan, Neil S., Schreiber, John R., Harding, Clifford V.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Microbial Immunity and Vaccines
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC97300/
https://ncbi.nlm.nih.gov/pubmed/10678959
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