Failure of Posaconazole Therapy in a Renal Transplant Patient with Invasive Aspergillosis Due to Aspergillus fumigatus with Attenuated Susceptibility to Posaconazole

We report the case of a kidney transplant recipient with invasive aspergillosis due to Aspergillus fumigatus resistant to voriconazole and intermediately susceptible to posaconazole who failed posaconazole therapy. Plasma posaconazole concentrations indicated an unfavorable ratio of the area under t...

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Autores principales: Kuipers, Saskia, Brüggemann, Roger J. M., de Sévaux, Ruud G. L., Heesakkers, John P. F. A., Melchers, Willem J. G., Mouton, Johan W., Verweij, Paul E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2011
Materias:
Clinical Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122456/
https://ncbi.nlm.nih.gov/pubmed/21502625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01544-10
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