Posaconazole Prophylaxis in Experimental Azole-Resistant Invasive Pulmonary Aspergillosis

We investigated the efficacy of posaconazole prophylaxis in preventing invasive aspergillosis due to azole-resistant Aspergillus fumigatus isolates. Using a neutropenic murine model of pulmonary infection, posaconazole prophylaxis was evaluated using three isogenic clinical isolates, with posaconazo...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Seyedmousavi, Seyedmojtaba, Mouton, Johan W., Melchers, Willem J. G., Verweij, Paul E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325774/
https://ncbi.nlm.nih.gov/pubmed/25534731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03850-14
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