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Molecular Mechanism of Renal Tubular Secretion of the Antimalarial Drug Chloroquine
The antimalarial drug chloroquine is eliminated to a significant extent by renal tubular secretion. The molecular mechanism of renal chloroquine secretion remains unknown. We hypothesized that organic cation transporter 2 (OCT2) and multidrug and toxin extrusion protein 1 (MATE1), localized in the b...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3122445/ https://ncbi.nlm.nih.gov/pubmed/21518836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01835-10 |
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