Alanine-glyoxylate aminotransferase 2 (AGXT2) Polymorphisms Have Considerable Impact on Methylarginine and β-aminoisobutyrate Metabolism in Healthy Volunteers

Elevated plasma concentrations of asymmetric (ADMA) and symmetric (SDMA) dimethylarginine have repeatedly been linked to adverse clinical outcomes. Both methylarginines are substrates of alanine-glyoxylate aminotransferase 2 (AGXT2). It was the aim of the present study to simultaneously investigate...

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Detalhes bibliográficos
Main Authors: Kittel, Anja, Müller, Fabian, König, Jörg, Mieth, Maren, Sticht, Heinrich, Zolk, Oliver, Kralj, Ana, Heinrich, Markus R., Fromm, Martin F., Maas, Renke
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933329/
https://ncbi.nlm.nih.gov/pubmed/24586340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088544
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