Diabetes-linked transcription factor HNF4α regulates metabolism of endogenous methylarginines and β-aminoisobutyric acid by controlling expression of alanine-glyoxylate aminotransferase 2

Elevated levels of circulating asymmetric and symmetric dimethylarginines (ADMA and SDMA) predict and potentially contribute to end organ damage in cardiovascular diseases. Alanine-glyoxylate aminotransferase 2 (AGXT2) regulates systemic levels of ADMA and SDMA, and also of beta-aminoisobutyric acid...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Burdin, Dmitry V., Kolobov, Alexey A., Brocker, Chad, Soshnev, Alexey A., Samusik, Nikolay, Demyanov, Anton V., Brilloff, Silke, Jarzebska, Natalia, Martens-Lobenhoffer, Jens, Mieth, Maren, Maas, Renke, Bornstein, Stefan R., Bode-Böger, Stefanie M., Gonzalez, Frank, Weiss, Norbert, Rodionov, Roman N.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067591/
https://ncbi.nlm.nih.gov/pubmed/27752141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35503
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars