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Identification of the Catalytic Mechanism and Estimation of Kinetic Parameters for Fumarase

The enzyme fumarase catalyzes the reversible hydration of fumarate to malate. The reaction catalyzed by fumarase is critical for cellular energetics as a part of the tricarboxylic acid cycle, which produces reducing equivalents to drive oxidative ATP synthesis. A catalytic mechanism for the fumarase...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mescam, Muriel, Vinnakota, Kalyan C., Beard, Daniel A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122171/
https://ncbi.nlm.nih.gov/pubmed/21498518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.214452
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