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Detailed Enzyme Kinetics in Terms of Biochemical Species: Study of Citrate Synthase

The compulsory-ordered ternary catalytic mechanism for two-substrate two-product enzymes is analyzed to account for binding of inhibitors to each of the four enzyme states and to maintain the relationship between the kinetic constants and the reaction equilibrium constant. The developed quasi-steady...

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Detalhes bibliográficos
Main Authors: Beard, Daniel A., Vinnakota, Kalyan C., Wu, Fan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266798/
https://ncbi.nlm.nih.gov/pubmed/18350161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001825
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