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Detailed Enzyme Kinetics in Terms of Biochemical Species: Study of Citrate Synthase
The compulsory-ordered ternary catalytic mechanism for two-substrate two-product enzymes is analyzed to account for binding of inhibitors to each of the four enzyme states and to maintain the relationship between the kinetic constants and the reaction equilibrium constant. The developed quasi-steady...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2266798/ https://ncbi.nlm.nih.gov/pubmed/18350161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001825 |
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