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Kinetic Analysis and Design of Experiments to Identify the Catalytic Mechanism of the Monocarboxylate Transporter Isoforms 4 and 1

Transport of lactate, pyruvate, and other monocarboxylates across the sarcolemma of skeletal and cardiac myocytes occurs via passive diffusion and by monocarboxylate transporter (MCT) mediated transport. The flux of lactate and protons through the MCT plays an important role in muscle energy metabol...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Vinnakota, Kalyan C., Beard, Daniel A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021679/
https://ncbi.nlm.nih.gov/pubmed/21244833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.11.079
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