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Determination of the Catalytic Mechanism for Mitochondrial Malate Dehydrogenase

The kinetics of malate dehydrogenase (MDH) catalyzed oxidation/reduction of L-malate/oxaloacetate is pH-dependent due to the proton generated/taken up during the reaction. Previous kinetic studies on the mitochondrial MDH did not yield a consensus kinetic model that explains both substrate and pH de...

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Publicat a:Biophys J
Autors principals: Dasika, Santosh K., Vinnakota, Kalyan C., Beard, Daniel A.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302198/
https://ncbi.nlm.nih.gov/pubmed/25606688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.11.3467
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