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Detailed Enzyme Kinetics in Terms of Biochemical Species: Study of Citrate Synthase

The compulsory-ordered ternary catalytic mechanism for two-substrate two-product enzymes is analyzed to account for binding of inhibitors to each of the four enzyme states and to maintain the relationship between the kinetic constants and the reaction equilibrium constant. The developed quasi-steady...

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Bibliografische gegevens
Hoofdauteurs: Beard, Daniel A., Vinnakota, Kalyan C., Wu, Fan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266798/
https://ncbi.nlm.nih.gov/pubmed/18350161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001825
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