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Genome-wide association studies of cerebral white matter lesion burden: the CHARGE Consortium

OBJECTIVE: White matter hyperintensities (WMH) detectable by magnetic resonance imaging (MRI)are part of the spectrum of vascular injury associated with aging of the brain and are thought to reflect ischemic damage to the small deep cerebral vessels. WMH are associated with an increased risk of cogn...

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Main Authors: Fornage, Myriam, Debette, Stephanie, Bis, Joshua C., Schmidt, Helena, Ikram, M. Arfan, Dufouil, Carole, Sigurdsson, Sigurdur, Lumley, Thomas, DeStefano, Anita L., Fazekas, Franz, Vrooman, Henri A., Shibata, Dean K., Maillard, Pauline, Zijdenbos, Alex, Smith, Albert V., Gudnason, Haukur, de Boer, Renske, Cushman, Mary, Mazoyer, Bernard, Heiss, Gerardo, Vernooij, Meike W., Enzinger, Christian, Glazer, Nicole L., Beiser, Alexa, Knopman, David S., Cavalieri, Margherita, Niessen, Wiro J., Harris, Tamara B., Petrovic, Katja, Lopez, Oscar L., Au, Rhoda, Lambert, Jean-Charles, Hofman, Albert, Gottesman, Rebecca F., Garcia, Melissa, Heckbert, Susan R., Atwood, Larry D., Catellier, Diane J., Uitterlinden, Andre G., Yang, Qiong, Smith, Nicholas L., Aspelund, Thor, Romero, Jose R., Rice, Kenneth, Taylor, Kent D., Nalls, Michael A., Rotter, Jerome I., Sharret, Richey, van Duijn, Cornelia M., Amouyel, Philippe, Wolf, Philip A., Gudnason, Vilmundur, van der Lugt, Aad, Boerwinkle, Eric, Psaty, Bruce M., Seshadri, Sudha, Tzourio, Christophe, Breteler, Monique M.B., Mosley, Thomas H., Schmidt, Reinhold, Longstreth, W.T., DeCarli, Charles, Launer, Lenore J.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122147/
https://ncbi.nlm.nih.gov/pubmed/21681796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22403
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