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Genome-wide association studies of cerebral white matter lesion burden: the CHARGE Consortium

OBJECTIVE: White matter hyperintensities (WMH) detectable by magnetic resonance imaging (MRI)are part of the spectrum of vascular injury associated with aging of the brain and are thought to reflect ischemic damage to the small deep cerebral vessels. WMH are associated with an increased risk of cogn...

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Main Authors: Fornage, Myriam, Debette, Stephanie, Bis, Joshua C., Schmidt, Helena, Ikram, M. Arfan, Dufouil, Carole, Sigurdsson, Sigurdur, Lumley, Thomas, DeStefano, Anita L., Fazekas, Franz, Vrooman, Henri A., Shibata, Dean K., Maillard, Pauline, Zijdenbos, Alex, Smith, Albert V., Gudnason, Haukur, de Boer, Renske, Cushman, Mary, Mazoyer, Bernard, Heiss, Gerardo, Vernooij, Meike W., Enzinger, Christian, Glazer, Nicole L., Beiser, Alexa, Knopman, David S., Cavalieri, Margherita, Niessen, Wiro J., Harris, Tamara B., Petrovic, Katja, Lopez, Oscar L., Au, Rhoda, Lambert, Jean-Charles, Hofman, Albert, Gottesman, Rebecca F., Garcia, Melissa, Heckbert, Susan R., Atwood, Larry D., Catellier, Diane J., Uitterlinden, Andre G., Yang, Qiong, Smith, Nicholas L., Aspelund, Thor, Romero, Jose R., Rice, Kenneth, Taylor, Kent D., Nalls, Michael A., Rotter, Jerome I., Sharret, Richey, van Duijn, Cornelia M., Amouyel, Philippe, Wolf, Philip A., Gudnason, Vilmundur, van der Lugt, Aad, Boerwinkle, Eric, Psaty, Bruce M., Seshadri, Sudha, Tzourio, Christophe, Breteler, Monique M.B., Mosley, Thomas H., Schmidt, Reinhold, Longstreth, W.T., DeCarli, Charles, Launer, Lenore J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122147/
https://ncbi.nlm.nih.gov/pubmed/21681796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22403
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