Genome-wide association studies of cerebral white matter lesion burden: the CHARGE Consortium

OBJECTIVE: White matter hyperintensities (WMH) detectable by magnetic resonance imaging (MRI)are part of the spectrum of vascular injury associated with aging of the brain and are thought to reflect ischemic damage to the small deep cerebral vessels. WMH are associated with an increased risk of cogn...

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Hlavní autoři: Fornage, Myriam, Debette, Stephanie, Bis, Joshua C., Schmidt, Helena, Ikram, M. Arfan, Dufouil, Carole, Sigurdsson, Sigurdur, Lumley, Thomas, DeStefano, Anita L., Fazekas, Franz, Vrooman, Henri A., Shibata, Dean K., Maillard, Pauline, Zijdenbos, Alex, Smith, Albert V., Gudnason, Haukur, de Boer, Renske, Cushman, Mary, Mazoyer, Bernard, Heiss, Gerardo, Vernooij, Meike W., Enzinger, Christian, Glazer, Nicole L., Beiser, Alexa, Knopman, David S., Cavalieri, Margherita, Niessen, Wiro J., Harris, Tamara B., Petrovic, Katja, Lopez, Oscar L., Au, Rhoda, Lambert, Jean-Charles, Hofman, Albert, Gottesman, Rebecca F., Garcia, Melissa, Heckbert, Susan R., Atwood, Larry D., Catellier, Diane J., Uitterlinden, Andre G., Yang, Qiong, Smith, Nicholas L., Aspelund, Thor, Romero, Jose R., Rice, Kenneth, Taylor, Kent D., Nalls, Michael A., Rotter, Jerome I., Sharret, Richey, van Duijn, Cornelia M., Amouyel, Philippe, Wolf, Philip A., Gudnason, Vilmundur, van der Lugt, Aad, Boerwinkle, Eric, Psaty, Bruce M., Seshadri, Sudha, Tzourio, Christophe, Breteler, Monique M.B., Mosley, Thomas H., Schmidt, Reinhold, Longstreth, W.T., DeCarli, Charles, Launer, Lenore J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122147/
https://ncbi.nlm.nih.gov/pubmed/21681796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22403
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