Potent Engineered PLGA Nanoparticles by Virtue of Exceptionally High Chemotherapeutic Loadings

Herein we report the fabrication of engineered poly(lactic acid-co-glycolic acid) nanoparticles via the PRINT(®) (Particle Replication In Non-wetting Templates) process with high and efficient loadings of docetaxel, up to 40% (w/w) with encapsulation efficiencies >90%. The PRINT process enables i...

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Bibliographic Details
Main Authors: Enlow, Elizabeth M., Luft, J. Christopher, Napier, Mary E., DeSimone, Joseph M.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122105/
https://ncbi.nlm.nih.gov/pubmed/21265552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl104117p
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