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Retinoic Acid-Loaded PLGA Nanoparticle Formulation of ApoB-100-Derived Peptide 210 Attenuates Atherosclerosis

We developed a vaccine formulation containing ApoB derived P210 peptides as autoantigens, retinoic acid (RA) as an immune enhancer, both of which were delivered using PLGA nanoparticles. The formula was used to induce an immune response in 12-week-old male Apoe(−/−) mice with pre-existing atheroscle...

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Detalhes bibliográficos
Publicado no:J Biomed Nanotechnol
Main Authors: Yi, Xianwen, Wang, Ying, Jia, Zhenquan, Hiller, Sylvia, Nakamura, Jun, Luft, J. Christopher, Tian, Shaomin, DeSimone, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034552/
https://ncbi.nlm.nih.gov/pubmed/32970979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1166/jbn.2020.2905
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