Mithramycin-loaded mPEG-PLGA nanoparticles exert potent antitumor efficacy against pancreatic carcinoma

Previous studies have shown that mithramycin A (MIT) is a promising candidate for the treatment of pancreatic carcinoma through inhibiting transcription factor Sp1. However, systemic toxicities may limit its clinical application. Here, we report a rationally designed formulation of MIT-loaded nanopa...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Liu, Xu-Jie, Li, Liang, Liu, Xiu-Jun, Li, Yi, Zhao, Chun-Yan, Wang, Rui-Qi, Zhen, Yong-Su
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533565/
https://ncbi.nlm.nih.gov/pubmed/28769562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S139507
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