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A Neoceptor Approach to Unraveling Microscopic Interactions between the Human A(2A) Adenosine Receptor and Its Agonists
Strategically mutated neoceptors, e.g., with anionic residues in TMs 3 and 7 intended for pairing with positively charged amine-modified nucleosides, were derived from the antiinflammatory A(2A) adenosine receptor (AR). Adenosine derivatives functionalized at the 5′, 2, and N(6) positions were synth...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2005
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3122079/ https://ncbi.nlm.nih.gov/pubmed/15734651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2004.12.010 |
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