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THE OCCUPANCY OF ENDOTHELIAL PROTEIN C RECEPTOR BY ITS LIGAND MODULATES THE PAR-1 DEPENDENT SIGNALING SPECIFICITY OF COAGULATION PROTEASES
Several recent studies have demonstrated that the activation of protease-activated receptor 1 (PAR-1) by thrombin and activated protein C (APC) on cultured vascular endothelial cells elicits paradoxical proinflammatory and antiinflammatory responses, respectively. Noting that the protective intracel...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3121899/ https://ncbi.nlm.nih.gov/pubmed/21438119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.447 |
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