Lipooligosaccharide is required for the generation of infectious elementary bodies in Chlamydia trachomatis

Lipopolysaccharides (LPS) and lipooligosaccharides (LOS) are the main lipid components of bacterial outer membranes and are essential for cell viability in most Gram-negative bacteria. Here we show that small molecule inhibitors of LpxC [UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc deacetylase], the enzyme...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Nguyen, Bidong D., Cunningham, Doreen, Liang, Xiaofei, Chen, Xin, Toone, Eric J., Raetz, Christian R. H., Zhou, Pei, Valdivia, Raphael H.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2011
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121853/
https://ncbi.nlm.nih.gov/pubmed/21628561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107478108
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