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Lipooligosaccharide is required for the generation of infectious elementary bodies in Chlamydia trachomatis
Lipopolysaccharides (LPS) and lipooligosaccharides (LOS) are the main lipid components of bacterial outer membranes and are essential for cell viability in most Gram-negative bacteria. Here we show that small molecule inhibitors of LpxC [UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc deacetylase], the enzyme...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3121853/ https://ncbi.nlm.nih.gov/pubmed/21628561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107478108 |
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