Lipooligosaccharide is required for the generation of infectious elementary bodies in Chlamydia trachomatis

Lipopolysaccharides (LPS) and lipooligosaccharides (LOS) are the main lipid components of bacterial outer membranes and are essential for cell viability in most Gram-negative bacteria. Here we show that small molecule inhibitors of LpxC [UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc deacetylase], the enzyme...

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書誌詳細
主要な著者: Nguyen, Bidong D., Cunningham, Doreen, Liang, Xiaofei, Chen, Xin, Toone, Eric J., Raetz, Christian R. H., Zhou, Pei, Valdivia, Raphael H.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2011
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121853/
https://ncbi.nlm.nih.gov/pubmed/21628561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107478108
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