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Lipooligosaccharide is required for the generation of infectious elementary bodies in Chlamydia trachomatis

Lipopolysaccharides (LPS) and lipooligosaccharides (LOS) are the main lipid components of bacterial outer membranes and are essential for cell viability in most Gram-negative bacteria. Here we show that small molecule inhibitors of LpxC [UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc deacetylase], the enzyme...

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Autors principals: Nguyen, Bidong D., Cunningham, Doreen, Liang, Xiaofei, Chen, Xin, Toone, Eric J., Raetz, Christian R. H., Zhou, Pei, Valdivia, Raphael H.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121853/
https://ncbi.nlm.nih.gov/pubmed/21628561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107478108
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