Lipooligosaccharide is required for the generation of infectious elementary bodies in Chlamydia trachomatis

Lipopolysaccharides (LPS) and lipooligosaccharides (LOS) are the main lipid components of bacterial outer membranes and are essential for cell viability in most Gram-negative bacteria. Here we show that small molecule inhibitors of LpxC [UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc deacetylase], the enzyme...

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Detalhes bibliográficos
Main Authors: Nguyen, Bidong D., Cunningham, Doreen, Liang, Xiaofei, Chen, Xin, Toone, Eric J., Raetz, Christian R. H., Zhou, Pei, Valdivia, Raphael H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121853/
https://ncbi.nlm.nih.gov/pubmed/21628561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107478108
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