Generation of a unique small molecule peptidomimetic that neutralizes lupus autoantibody activity

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the presence of pathogenic autoantibodies, many of which are directed against nuclear antigens, in particular double-stranded (ds) DNA. Both clinical studies and animal models have shown that anti-dsDNA antibodies co...

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Bibliografiske detaljer
Main Authors: Bloom, Ona, Cheng, Kai Fan, He, Mingzhu, Papatheodorou, Angelos, Volpe, Bruce T., Diamond, Betty, Al-Abed, Yousef
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121823/
https://ncbi.nlm.nih.gov/pubmed/21646518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103555108
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