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Generation of a unique small molecule peptidomimetic that neutralizes lupus autoantibody activity
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the presence of pathogenic autoantibodies, many of which are directed against nuclear antigens, in particular double-stranded (ds) DNA. Both clinical studies and animal models have shown that anti-dsDNA antibodies co...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3121823/ https://ncbi.nlm.nih.gov/pubmed/21646518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103555108 |
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