Amending HIV Drugs: A Novel Small-Molecule Approach To Target Lupus Anti-DNA Antibodies

Systemic lupus erythematosus is an autoimmune disease that can affect numerous tissues and is characterized by the production of nuclear antigen-directed autoantibodies (e.g., anti-dsDNA). Using a combination of virtual and ELISA-based screens, we made the intriguing discovery that several HIV-prote...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: VanPatten, Sonya, Sun, Shan, He, Mingzhu, Cheng, Kai Fan, Altiti, Ahmad, Papatheodorou, Angelos, Kowal, Czeslawa, Jeganathan, Venkatesh, Crawford, James M., Bloom, Ona, Volpe, Bruce T., Grant, Christian, Meurice, Nathalie, Coleman, Thomas R., Diamond, Betty, Al-Abed, Yousef
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592695/
https://ncbi.nlm.nih.gov/pubmed/27603688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.6b00694
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