Quantitative Analyses of Cryptochrome-mBMAL1 Interactions: MECHANISTIC INSIGHTS INTO THE TRANSCRIPTIONAL REGULATION OF THE MAMMALIAN CIRCADIAN CLOCK

The mammalian cryptochromes mCRY1 and mCRY2 act as transcriptional repressors within the 24-h transcription-translational feedback loop of the circadian clock. The C-terminal tail and a preceding predicted coiled coil (CC) of the mCRYs as well as the C-terminal region of the transcription factor mBM...

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Détails bibliographiques
Auteurs principaux: Czarna, Anna, Breitkreuz, Helena, Mahrenholz, Carsten C., Arens, Julia, Strauss, Holger M., Wolf, Eva
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Gene Regulation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121388/
https://ncbi.nlm.nih.gov/pubmed/21521686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.244749
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