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Cycling of CRYPTOCHROME Proteins Is Not Necessary for Circadian-Clock Function in Mammalian Fibroblasts

BACKGROUND: An interlocked transcriptional-translational feedback loop (TTFL) is thought to generate the mammalian circadian clockwork in both the central pacemaker residing in the hypothalamic suprachiasmatic nuclei and in peripheral tissues. The core circadian genes, including Period1 and Period2...

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Detalhes bibliográficos
Main Authors: Fan, Yunzhen, Hida, Akiko, Anderson, Daniel A., Izumo, Mariko, Johnson, Carl Hirschie
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434691/
https://ncbi.nlm.nih.gov/pubmed/17583506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2007.05.048
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