Cycling of CRYPTOCHROME Proteins Is Not Necessary for Circadian-Clock Function in Mammalian Fibroblasts

BACKGROUND: An interlocked transcriptional-translational feedback loop (TTFL) is thought to generate the mammalian circadian clockwork in both the central pacemaker residing in the hypothalamic suprachiasmatic nuclei and in peripheral tissues. The core circadian genes, including Period1 and Period2...

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Hauptverfasser: Fan, Yunzhen, Hida, Akiko, Anderson, Daniel A., Izumo, Mariko, Johnson, Carl Hirschie
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434691/
https://ncbi.nlm.nih.gov/pubmed/17583506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2007.05.048
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