Intravaginal immunization using the recombinant HIV-1 clade-C trimeric envelope glycoprotein CN54gp140 formulated within lyophilized solid dosage forms

Vaccine-mediated prevention of primary HIV-1 infection at the heterosexual mucosal portal of entry may be facilitated by highly optimised formulations or drug delivery devices for intravaginal (i.vag) immunization. Previously we described hydroxyethylcellulose (HEC)-based rheologically structured ge...

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Autors principals: Donnelly, Louise, Curran, Rhonda M., Tregoning, John S., McKay, Paul F., Cole, Tom, Morrow, Ryan J., Kett, Vicky L., Andrews, Gavin P., Woolfson, A. David, Malcolm, R. Karl, Shattock, Robin J.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Science 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120965/
https://ncbi.nlm.nih.gov/pubmed/21514349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.04.023
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