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Functional Role of Dimerization of Human Peptidylarginine Deiminase 4 (PAD4)

Peptidylarginine deiminase 4 (PAD4) is a homodimeric enzyme that catalyzes Ca(2+)-dependent protein citrullination, which results in the conversion of arginine to citrulline. This paper demonstrates the functional role of dimerization in the regulation of PAD4 activity. To address this question, we...

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Bibliografski detalji
Glavni autori: Liu, Yi-Liang, Chiang, Yu-Hsiu, Liu, Guang-Yaw, Hung, Hui-Chih
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120853/
https://ncbi.nlm.nih.gov/pubmed/21731701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021314
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