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Functional Role of Dimerization of Human Peptidylarginine Deiminase 4 (PAD4)
Peptidylarginine deiminase 4 (PAD4) is a homodimeric enzyme that catalyzes Ca(2+)-dependent protein citrullination, which results in the conversion of arginine to citrulline. This paper demonstrates the functional role of dimerization in the regulation of PAD4 activity. To address this question, we...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3120853/ https://ncbi.nlm.nih.gov/pubmed/21731701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021314 |
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