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Development of Mouse Hepatocyte Lines Permissive for Hepatitis C Virus (HCV)

The lack of a suitable small animal model for the analysis of hepatitis C virus (HCV) infection has hampered elucidation of the HCV life cycle and the development of both protective and therapeutic strategies against HCV infection. Human and mouse harbor a comparable system for antiviral type I inte...

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Detalhes bibliográficos
Main Authors: Aly, Hussein Hassan, Oshiumi, Hiroyuki, Shime, Hiroaki, Matsumoto, Misako, Wakita, Taka, Shimotohno, Kunitada, Seya, Tsukasa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120852/
https://ncbi.nlm.nih.gov/pubmed/21731692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021284
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