Interferon (IFN) and Cellular Immune Response Evoked in RNA-Pattern Sensing During Infection with Hepatitis C Virus (HCV)

Hepatitis C virus (HCV) infects hepatocytes but not dendritic cells (DCs), but DCs effectively mature in response to HCV-infected hepatocytes. Using gene-disrupted mice and hydrodynamic injection strategy, we found the MAVS pathway to be crucial for induction of type III interferons (IFNs) in respon...

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Bibliografiske detaljer
Udgivet i:Sensors (Basel)
Main Authors: Nakai, Masato, Oshiumi, Hiroyuki, Funami, Kenji, Okamoto, Masaaki, Matsumoto, Misako, Seya, Tsukasa, Sakamoto, Naoya
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634469/
https://ncbi.nlm.nih.gov/pubmed/26512676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/s151027160
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