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Connexin 43 signaling enhances the generation of Foxp3(+) regulatory T cells

Despite their importance for the functioning of the immune system, thymic development and peripheral maintenance of Foxp3(+) regulatory (T(R)) cells are poorly understood. We have found that connexin 43 (C×43), expressed by thymic T(R) cells progenitors, supports T(R) development. Mice with deletion...

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Autors principals: Kuczma, Michal, Lee, Jeffrey R., Kraj, Piotr
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119766/
https://ncbi.nlm.nih.gov/pubmed/21642545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003785
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