Skeletal Involution by Age-associated Oxidative Stress and Its Acceleration by Loss of Sex Steroids

Both aging and loss of sex steroids have adverse effects on skeletal homeostasis, but whether and how they may influence each others negative impact on bone remains unknown. We report herein that both female and male C57BL/6 mice progressively lost strength (as determined by load-to-failure measurem...

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Autors principals: Almeida, Maria, Han, Li, Martin-Millan, Marta, Plotkin, Lilian I., Stewart, Scott A., Roberson, Paula K., Kousteni, Stavroula, O’Brien, Charles A., Bellido, Teresita, Parfitt, A. Michael, Weinstein, Robert S., Jilka, Robert L., Manolagas, Stavros C.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119455/
https://ncbi.nlm.nih.gov/pubmed/17623659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M702810200
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