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Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids
It has been found that 4-estren-3α,17β-diol, a synthetic ligand for the estrogen receptor (ER) or androgen receptor (AR), which does not affect classical transcription, reverses bone loss in ovariectomized females or orchidectomized males without affecting the uterus or seminal vesicles, demonstrati...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC156107/ https://ncbi.nlm.nih.gov/pubmed/12782668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317261 |
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