Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids

It has been found that 4-estren-3α,17β-diol, a synthetic ligand for the estrogen receptor (ER) or androgen receptor (AR), which does not affect classical transcription, reverses bone loss in ovariectomized females or orchidectomized males without affecting the uterus or seminal vesicles, demonstrati...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Kousteni, Stavroula, Han, Li, Chen, Jin-Ran, Almeida, Maria, Plotkin, Lilian I., Bellido, Teresita, Manolagas, Stavros C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2003
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156107/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12782668/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI17261
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