Skeletal Involution by Age-associated Oxidative Stress and Its Acceleration by Loss of Sex Steroids

Both aging and loss of sex steroids have adverse effects on skeletal homeostasis, but whether and how they may influence each others negative impact on bone remains unknown. We report herein that both female and male C57BL/6 mice progressively lost strength (as determined by load-to-failure measurem...

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Detalhes bibliográficos
Main Authors: Almeida, Maria, Han, Li, Martin-Millan, Marta, Plotkin, Lilian I., Stewart, Scott A., Roberson, Paula K., Kousteni, Stavroula, O’Brien, Charles A., Bellido, Teresita, Parfitt, A. Michael, Weinstein, Robert S., Jilka, Robert L., Manolagas, Stavros C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119455/
https://ncbi.nlm.nih.gov/pubmed/17623659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M702810200
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