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Chronic Exposure to a High-Fat Diet Induces Hepatic Steatosis, Impairs Nitric Oxide Bioavailability, and Modifies the Mitochondrial Proteome in Mice

Obesity-related pathologies, such as nonalcoholic fatty liver disease, are linked to mitochondrial dysfunction and nitric oxide (NO) deficiency. Herein, we tested the hypothesis that a high-fat diet (HFD) modifies the liver mitochondrial proteome and alters proteins involved in NO metabolism, namely...

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Bibliografiset tiedot
Päätekijät: Eccleston, Heather B., Andringa, Kelly K., Betancourt, Angela M., King, Adrienne L., Mantena, Sudheer K., Swain, Telisha M., Tinsley, Heather N., Nolte, Ryan N., Nagy, Tim R., Abrams, Gary A., Bailey, Shannon M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Mary Ann Liebert, Inc. 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118652/
https://ncbi.nlm.nih.gov/pubmed/20919931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3395
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