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PHOSPHORYLATION AT SERINE 208 OF THE 1α,25-DIHYDROXY VITAMIN D3 RECEPTOR MODULATES THE INTERACTION WITH TRANSCRIPTIONAL COACTIVATORS
Upon ligand binding the 1α,25-dihydroxy vitamin D3 receptor (VDR) undergoes a conformational change that allows interaction with coactivator proteins including p160/SRC family members and the multimeric DRIP complex through the DRIP205 subunit. Casein kinase II (CKII) phosphorylates VDR both in vitr...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3118558/ https://ncbi.nlm.nih.gov/pubmed/17368182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2006.12.021 |
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