Use of cytokine immunotherapy to block CNS demyelination induced by a recombinant HSV-1 expressing IL-2

We previously have described a model of MS in which constitutive expression of murine IL-2 by HSV-1 (HSV-IL-2) causes CNS demyelination in different strains of mice (Zandian et al 2009, IOVS, 50:3275). In the current study, we investigated whether this HSV-IL-2-induced demyelination can be blocked u...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zandian, Mandana, Mott, Kevin R., Allen, Sariah J, Dumitrascu, Oana, Kuo, Jane Z, Ghiasi, Homayon
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118258/
https://ncbi.nlm.nih.gov/pubmed/21412284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2011.32
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