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A comparative study of experimental mouse models of central nervous system demyelination

Several mouse models of multiple sclerosis (MS) are now available. We have established a mouse model, in which ocular infection with a recombinant HSV-1 that expresses murine IL-2 constitutively (HSV-IL-2) causes CNS demyelination in different strains of mice. This model differs from most other mode...

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Main Authors: Dumitrascu, Oana M., Mott, Kevin R., Ghiasi, Homayon
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047154/
https://ncbi.nlm.nih.gov/pubmed/24718267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2014.33
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